MathMan 2: This game is nothing like the first version of Math Man (similar to Pac-Man) that you can see on the net.
First of all, in this one - you're flying - which is cool! You can customize the difficulty so it's convenient for almost everyone. But spoiler here: negative numbers included!
Anyway, the instructions are:
choose the speed of the game (left hand side of the game screen)
strike at the sensitive point - correct result of equation
avoid false results (you lose health)
control mathman with arrows or A,D,W,S
freeze time using space if necessary
set the maximum result of the equation (bottom of the game screen)
start the game at the bottom left corner
I got to level 8 and got pierced like a cheese by some flying stinger thing. :-)